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HLA Imputation: the verdict is not guilty.

It is my opinion that 28th EFI conference poster P225
EVALUATION OF IMPUTATION METHODS FOR CLASSICAL HLA-DRB1 USING A
FINNISH DATASET
would have deserved selection for oral presentation to give it a broader audience, and pass an important message.

Anyway, this Finnish study shows, by using data obtained independently of the imputation study, that only 25% of alleles are correctly imputed. In other words; imputation is disproved.

Now it is time to enjoy Stockholm.

A Skål to the organisers!


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