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Eurostam final meeting and epitope workshop

The last meeting of EUROSTAM (A Europe-wide strategy to enhance transplantation of highly sensitized patients on basis of Acceptable HLA mismatches, http://eurostam.eu/) took place in Leiden from 18th to 20th of November 2015. It included a workshop on the current status of the definition of HLA epitopes and their clinical relevance.

The Pheno Search utility developed in Geneva as part of this project was presented at the Regentenkamer (see picture below). This tool allow to output HLA phenotypes frequencies in different European populations (including complex search expressions).

Eurostam_Leiden

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International summer school on immunogenetics

The HLA-net bioinformatics platform was recently presented in a talk given during the 11th International Summer School on Immunogenetics (15-18 October, 2014). The school was organized by ASHI (American Society for Histocompatibility and Immunogenetics) with support from EFI (European Federation for Immunogenetics) and APHIA (Asia-Pacific Histocompatibility and Immunogenetics Association) in Boulder at the foothills of the Rocky Mountains.

Close to 50 participants from all over the world attended the meeting as shown on this souvenir pic.

ISS 2014_Boulder

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Population Genetics at EFI in Stockholm

A report of the Population Genetics/Anthropology session of the latest EFI congress in Stockholm has been published in the EFI newsletter of this month.

The collaborative HLA-net study on a new HLA map of Europe was among the abstracts presented during this session, among many other very interesting talks. Discover more about this session and the rest of the congress in the newsletter.

Including some social event pics like the one below at the Welcome reception in the beautiful and golden Stockholm City Hall.

EFI_Stockholm

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Summertime

The 28th EFI conference seems now faraway, yet for us summertime still not here.

The days are getting already getting shorter and, before they get too short, we finally upload two photos from the session were HLA-net became public.

IMG_5814

The session started right in time, after lunch, and lasted long, but participants were so brave that they resisted to sleep.

open meeting photo

Or so we believe.

With this souvenir we thank to all participants, present or not. If summer is not too bad, a few new gadgets will be on the site by the end of August. Until then; have a nice summer.

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HLA Imputation: the verdict is not guilty.

It is my opinion that 28th EFI conference poster P225
EVALUATION OF IMPUTATION METHODS FOR CLASSICAL HLA-DRB1 USING A
FINNISH DATASET would have deserved selection for oral presentation to give it a broader audience, and pass an important message.

Anyway, this Finnish study shows, by using data obtained independently of the imputation study, that only 25% of alleles are correctly imputed. In other words; imputation is disproved.

Now it is time to enjoy Stockholm.

A Skål to the organisers!

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New special issue of Human Heredity /// Genetic Diversity in European Populations: Evolutionary Evidence and Medical Implications

Cover_Human_Heredity_76_3-4_2013

A special issue of Human Heredity entitled “Genetic Diversity in European Populations: Evolutionary Evidence and Medical Implications” has just been published. It has been stimulated by a scientific meeting held in Geneva, Switzerland, in January 2013 as the closing conference of the European COST Action (BM0803, HLA-NET), also supported by the Swiss National Science Foundation.

www.karger.ch/Book/Home/261488

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Hard Work in Athens

Although most people would see an oxymoron in the title, we can swear it is not the case. Of course, the weather is terrific, we could not taste all the wonderful “petit plats” people presented to us, the view of the Ακρόπολη Αθηνών is magnificent (though we can’t see it from the meeting room, only from the bar), but the server breakage stressed us a lot and made our nights not so sleepy. But it’s done!

And our first HLA-net server emergency ended up quite well.

Thanks to all in Geneva.

royal-olympic-restaurant

στην υγειά μας

Contact

Prof. Alicia Sanchez-Mazas
Dept. of Genetics & Evolution
alicia.sanchez-mazas@unige.ch

HLA-net is an European network of the HLA diversity for histocompatibility, clinical transplantation, epidemiology and population genetics.